Synthesis and Study of 1,2,4-Triazine and Thiadiazoles Based Derivatives of S-Triazine as Antimicrobial Agents
نویسندگان
چکیده
منابع مشابه
Synthesis of s-triazine-based thiazolidinones as antimicrobial agents.
A novel series of thiazolidinone derivatives, namely 4-{4-dimethylamino-6-[4-oxo-2-phenyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-thiazolidin-3-yl]-[1,3,5]-triazin-2-yloxy}-1-methyl-1H-quinolin-2-ones, have been synthesized from the key intermediate 4-(4-amino-6-dimethylamino-[1,3,5]-triazin-2-yloxy)-1-methyl-1H-quinolin-2-one (5). Compound 5 was condensed with various aldehydes to give Schiff ...
متن کاملSynthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents.
Base catalysed condensation of ketone 5 with different aldehydes give chalcones, 2.4-bis-(phenylamino)-6-[4'-{3''-(4'''-substituted phenyl/2'''-furanyl/2'''-thienyl)-2''-propenon-1''-yl}phenylamino]-s-thriazines 6a-e. These chalcones on cyclization with hydrazine hydrate in the presence of glacial acetic acid, guanidine nitrate in the presence of alkali and malononitrile in the presence of ammo...
متن کاملSynthesis of novel aliphatic thiourea derivatives containing s-triazine moiety as potential antimicrobial agents
A new series of aliphatic thiourea and various aryl urea incorporating 1,3,5-s-triazine moiety is reported. This series has been obtained by the reaction of cyanuric chloride with thiophene-2-ethyl thiourea 1. Thus, the prepared 2-(thiophene-2ethyl thioureido)-4,6-dichloro-s-triazine 2 has been subsequently treated with morpholine to get 2-(thiophene-2-ethyl thioureido)-4-(morpholino)-6-chloro-...
متن کاملSynthesis of 1,2,4-triazine derivatives as potential anti-anxiety and anti-inflammatory agents.
A series of 1,2,4-triazine derivatives Va (1-24) and Vb (1-24) were synthesized and evaluated for their anti-anxiety and anti-inflammatory activities. The structures of the synthesized compounds were confirmed on the basis of their spectral data. Many of the triazine compounds were found to possess good activity. Especially, compounds bearing the sulfur atom showed better activity than those be...
متن کاملNitrogen-14 NQR in s-Triazine Derivatives*
Within a study of the temperature dependence of NQR frequencies in some s-triazine derivatives [1], resonance frequencies at 4.2 K were determined in melamine, cyanuric acid, and cyanuric chloride. New lines, which were not reported so far, were detected in two of these compounds. In melamine, nine more lines were found as already described in [4], In cyanuric chloride, two more lines were foun...
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ژورنال
عنوان ژورنال: Journal of Asian Scientific Research
سال: 2017
ISSN: 2226-5724,2223-1331
DOI: 10.18488/journal.2.2017.76.214.223